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Research Projects
Theoretical Modeling of Porosity of Surgical Fabrics for Tissue Ingrowth
Surgical fabrics have been used as vascular grafts, suture
rings of artificial heart valves, body wall/hernia repair, and
substrates for tissue engineering. All these applications require
a wide range of porosity for tissue ingrowth.
The objective of this project is to discover some magic formula
to theoretically determine the porosity of surgical fabrics
before they are actually made so that investigators/manufacturers
could design surgical fabrics of desirable porosity intelligently
instead of using trial/error approach.
We have developed a DOS-based computer program that can calculate
the theoretical porosity of woven and knitted fabrics based on
the user's inputs of fiber, yarn and fabric parameters.
C. C. Chu and J. Rawlinson, "Mathematical Modeling of Water
Permeability of Surgical Fabrics for Vascular Use."
J. Biomed. Mater. Res., 28(4):441-448 (1994).
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